An active magazine disengagement structure includes: a magazine body, adapted to be in engagement with at least one gun body; at least one trigger device, movably configured on the magazine body; at least one trigger device, movably configured on the magazine body, and positioned on one side of the trigger device and operated in coordination therewith; and at least one on-off device, movably configured on the magazine body, adapted to retain the magazine body with the gun body, and positioned on one side of the interlocking device and operated in coordination therewith to allow the magazine body to be separated from the gun body actively without any manual operation.