A network node (200), a wireless device (202) and methods therein, for handling device capabilities. The wireless device (202) sends (2:1) a capability pointer to the network node (200), which capability pointer is associated with a capability configuration of the wireless device (202). The network node (200) then retrieves (2:2) said capability configuration based on the capability pointer from a capability database (204) or the like where a range of predefined capability configurations and associated capability pointers are maintained. The retrieved capability configuration can then be used in radio communication (2:3) with the wireless device (202).