There are provided a liveness detection method and device. The liveness detection method comprises: generating a random action instruction sequence including at least one random action instruction; sequentially sending a random action instruction in the random action instruction sequence; and determining whether the sequentially sent random action instruction in the random action instruction sequence is sequentially executed by a living body based on detection information of at least two sensors, wherein the at least two sensors comprise an image sensor and at least one non-image sensor; and determining that the liveness detection is succeeded if the sequentially sent random action instruction in the random action instruction sequence is sequentially executed by the living body. Accuracy of liveness detection can be improved by adopting the random action sequence and by combining images captured by the image sensor and information detected by the non-image sensor.