Invention Grant
- Patent Title: Systems and methods for identifying cancer treatments from normalized biomarker scores
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Application No.: US16006279Application Date: 2018-06-12
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Publication No.: US10340030B2Publication Date: 2019-07-02
- Inventor: Alexander Bagaev , Feliks Frenkel , Ravshan Ataullakhanov
- Applicant: BostonGene Corporation
- Applicant Address: US MA Lincoln
- Assignee: BostonGene Corporation
- Current Assignee: BostonGene Corporation
- Current Assignee Address: US MA Lincoln
- Agency: Wolf, Greenfield & Sacks, P.C.
- Main IPC: G16B45/00
- IPC: G16B45/00 ; G16H50/30 ; C12Q1/6886 ; G16H50/20 ; G16H50/70 ; G06F16/28 ; G16B5/00 ; G16B20/00 ; G16B40/00 ; G16B50/00 ; G06F17/18 ; G16H20/00 ; G16H50/50 ; G16H20/10 ; G16H20/40 ; G16H70/20 ; G16H10/20

Abstract:
Techniques for generating therapy biomarker scores and visualizing same. The techniques include determining, using a patient's sequence data and distributions of biomarker values across one or more reference populations, a first set of normalized scores for a first set of biomarkers associated with a first therapy, and a second set of normalized scores for a second set of biomarkers associated with a second therapy, generating a graphical user interface (GUI) including a first portion associated with the first therapy and having at least one visual characteristic determined based on a normalized score of the respective biomarker in the first set of normalized scores; and a second portion associated with a second therapy and having at least one visual characteristic determined based on a normalized score of the respective biomarker in the second set of normalized scores; and displaying the generated GUI.
Public/Granted literature
- US20180358128A1 SYSTEMS AND METHODS FOR IDENTIFYING CANCER TREATMENTS FROM NORMALIZED BIOMARKER SCORES Public/Granted day:2018-12-13
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