A compression garment having a sealable bladder pocket adapted for applying compression therapy to a selected body part of a patient. The compression garment includes a selectively inflatable bladder and a wrap having a selectively sealable pocket. The pocket has a sealable main opening sized for passing the bladder therethrough for inserting the bladder in the pocket and removing the bladder from the pocket. A connector on the bladder may be connected to a fluid supply line via the main opening. In other embodiments, the connector may be connected in fluid communication with the fluid supply line via a secondary opening separated from the main opening. Fluid is delivered from the fluid source to an inflatable interior of the bladder to impart compression therapy to the body part.