Invention Grant
- Patent Title: Cationic lipid
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Application No.: US14412069Application Date: 2013-07-08
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Publication No.: US10342758B2Publication Date: 2019-07-09
- Inventor: Takeshi Kuboyama , Tomohiro Era , Tomoyuki Naoi , Kaori Yagi , Shintaro Hosoe
- Applicant: Kyowa Hakko Kirin Co., Ltd.
- Applicant Address: JP Tokyo
- Assignee: KYOWA HAKKO KIRIN CO., LTD.
- Current Assignee: KYOWA HAKKO KIRIN CO., LTD.
- Current Assignee Address: JP Tokyo
- Agency: Wenderoth, Lind & Ponack, L.L.P
- Priority: JP2012-152423 20120706; JP2013-092327 20130425
- International Application: PCT/JP2013/068682 WO 20130708
- International Announcement: WO2014/007398 WO 20140109
- Main IPC: A61K9/00
- IPC: A61K9/00 ; A61K9/51 ; A61K47/16 ; A61K47/54 ; C12N15/11 ; C12N15/88 ; A61K31/713 ; C07C211/21 ; C07C215/08 ; C07C215/10 ; C07C217/08 ; C07C229/12 ; C07C237/06 ; C07C271/12 ; C07C271/16 ; C07D207/06 ; C07D207/08 ; C07D207/09 ; C07D211/06 ; C07D211/22 ; A61K31/7088

Abstract:
Provided are a cationic lipid which facilitates the introduction of a nucleic acid into, for example, a cell or the like; a composition containing the cationic lipid and a nucleic acid; a method for introducing a nucleic acid into a cell by using a composition containing the cationic lipid and the nucleic acid; and the like. The cationic lipid is, for example, a cationic lipid represented by formula (A): formula (A): (wherein R1 is alkenyl or the like, R2 is alkenyl or the like, R3 and R4 are each alkyl, or are combined together to form alkylene, or R3 and R5 are combined together to form alkylene, R5 is a hydrogen atom or the like, or is combined together with R3 to form alkylene, X1 is alkylene, and X2 is a single bond or alkylene).
Public/Granted literature
- US20150174261A1 CATIONIC LIPID Public/Granted day:2015-06-25
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