A conjugate of a titanium dioxide nanomaterial and nanoparticulate herbal and/or fruit extracts is synthesized by impregnation, using titanium dioxide as support, to which are adsorbed organic functional groups, inorganic radicals and plant extracts that confer thereon anti-microbial properties with high disinfectant and antiseptic power, removing bacteria, fungi, mycobacteria, spores, mycobacteria, protozoa and viruses. The conjugate is a solid nanomaterial in liquid suspension and is prepared by impregnation to disperse the functional groups and the extract particles, with temperature control to stabilize the interactions within the network of the support. Virucidal, bactericidal, fungicidal, mycobactericidal, mycoplasmicidal, antiprotozoal and sporicidal activity of the nanoparticulate biomaterial depends on the particle size of the support oxide, the functionalization and the dispersion of extracts adsorbed on the surface. The functional groups may include hydroxyl, carboxyl, amine, sulfate, phosphate, and the supports may be titanium dioxide, silica, zirconia, zinc oxide, alumina and other metal oxides.