Invention Grant
- Patent Title: Engineered and multimerized human immunodeficiency virus envelope glycoproteins and uses thereof
-
Application No.: US15561438Application Date: 2016-03-24
-
Publication No.: US10342863B2Publication Date: 2019-07-09
- Inventor: Roland K. Strong , Colin Correnti , Leonidas Stamatatos , Andrew McGuire
- Applicant: Fred Hutchinson Cancer Research Center
- Applicant Address: US WA Seattle
- Assignee: Fred Hutchinson Cancer Research Center
- Current Assignee: Fred Hutchinson Cancer Research Center
- Current Assignee Address: US WA Seattle
- Agency: Lee & Hayes PC
- Agent C. Rachal Winger
- International Application: PCT/US2016/023985 WO 20160324
- International Announcement: WO2016/154422 WO 20160929
- Main IPC: A61K39/21
- IPC: A61K39/21 ; C12N7/04 ; A61K39/12 ; C07K14/005 ; C07K14/16 ; A61P31/18
Abstract:
Multimerized human immunodeficiency virus (HIV) envelope glycoproteins are described. The envelope glycoproteins are multimerized Engineered and multimerized human immunodeficiency virus (HIV) envelope glycoproteins are described. The envelope glycoproteins can be multimerized using a heptamerization domain such as a C4b binding protein multimerization domain or a ferritin fusion. The engineered and multimerized envelope glycoproteins can derived from glycoprotein 120 (gp 120) and can used as an HIV vaccine.
Public/Granted literature
- US20180117140A1 ENGINEERED AND MULTIMERIZED HUMAN IMMUNODEFICIENCY VIRUS ENVELOPE GLYCOPROTEINS AND USES THEREOF Public/Granted day:2018-05-03
Information query
