An occlusion clearing device and system for removing material from an artificial tube in situ includes a clearing stem having aspiration and irrigation conduits, where the irrigation conduit is disposed interior to, and terminates within the aspiration conduit. Material enters the clearing stem through aspiration, and irrigation is provided within the aspiration conduit to assist in aspiration through the clearing stem. A handset includes aspiration and irrigation tubing connecting to sources therefor, and further includes valves to control the flow through the tubing and conduits. These valves may be operated simultaneously with an actuator located on the handset, which may be done with one hand. A coupler at the operative end allows the clearing stem to gain access to the artificial tube for clearing while maintaining a closed system with a ventilator. Reciprocating motion may be generated and provided to the clearing stem to aid in occlusion removal.