- Patent Title: Process for the separation of enantiomers of piperazine derivatives
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Application No.: US16078715Application Date: 2017-02-24
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Publication No.: US10344021B2Publication Date: 2019-07-09
- Inventor: Anna Quattropani , Santosh S. Kulkarni , Awadut Gajendra Giri , Johannes Nicolaas Koek
- Applicant: Asceneuron SA
- Applicant Address: CH Lausanne
- Assignee: Asceneuron S A
- Current Assignee: Asceneuron S A
- Current Assignee Address: CH Lausanne
- Agency: Cooley LLP
- Agent Ivor R. Elrifi; Thomas J. Paxton
- Priority: IN201621006637 20160225
- International Application: PCT/EP2017/054272 WO 20170224
- International Announcement: WO2017/144635 WO 20170831
- Main IPC: C07D405/06
- IPC: C07D405/06 ; C07B57/00
Abstract:
The invention relates to a process for preparing either enantiomer of a compound of formula (I), wherein X, Y and n have the meaning given in claim 1, with high enantiomeric excess (e.e.), by chiral resolution in the presence of a non-racemic, chiral acid.
Public/Granted literature
- US20190062316A1 PROCESS FOR THE SEPARATION OF ENANTIOMERS OF PIPERAZINE DERIVATIVES Public/Granted day:2019-02-28
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