Invention Grant
- Patent Title: De-mannosylation of phosphorylated N-glycans
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Application No.: US15594256Application Date: 2017-05-12
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Publication No.: US10344310B2Publication Date: 2019-07-09
- Inventor: Kathleen Camilla Telesphore Alida Maria Piens , Wouter Vervecken
- Applicant: Oxyrane UK Limited , VIB vzw , Universiteit Gent
- Applicant Address: GB Manchester BE Ghent BE Ghent
- Assignee: Oxyrane UK Limited,VIB vzw,Universiteit Gent
- Current Assignee: Oxyrane UK Limited,VIB vzw,Universiteit Gent
- Current Assignee Address: GB Manchester BE Ghent BE Ghent
- Agency: Fish & Richardson P.C.
- Main IPC: C12P21/00
- IPC: C12P21/00 ; C12N15/80
Abstract:
Methods for demannosylating phosphorylated N-glycans on a glycoprotein are described that use a mannosidase capable of hydrolyzing a terminal alpha-1,2 mannose linkage when the underlying mannose is phosphorylated.
Public/Granted literature
- US20170306379A1 De-mannosylation of phosphorylated N-glycans Public/Granted day:2017-10-26
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