The present application relates to the structure of a load-bearing column and a factory using the same. The load-bearing columns comprise a first column, a second column and a third column. The first column is a reinforced concrete column and is arranged on the underground floor. The second column is a pre-fabricated reinforced concrete column on the ground floor and is fixed to the top of the first column. The third column is fixed to the top of the second column, wherein the third column comprises a steel column and a third reinforcing bar assembly which surrounds the circumference of the steel column and extends from the bottom of the steel column in an axial direction to a predetermined distance.