An Input/Output (I/O) adapter device coupled to a host device can perform data mirroring or data striping of payload data for transmitting to multiple network destinations. In some embodiments, a virtual machine running on the host device or on the I/O adapter device may be aware of the capabilities of the I/O adapter device to perform data mirroring or data striping and configure the I/O adapter device for performing data mirroring or data striping operations. In some embodiments, a virtual machine may be agnostic to the capabilities of the I/O adapter device to perform data mirroring or data striping and the I/O adapter device may perform data mirroring or data striping “under the hood” or without being configured by the virtual machine.