Cross-domain integration within product lifecycle management can include providing a plurality of finite state machines (FSMs), wherein each FSM is associated with one business object of an integration flow between a first enterprise information system and a second enterprise information system. Each FSM defines a plurality of lifecycle states of the associated business object. A business rule can be associated with each lifecycle state of each FSM. For each FSM, the associated business rules are independent of the FSM. For a selected lifecycle state of each FSM, the associated business rule defines a condition causing a transition from the selected lifecycle state to a next lifecycle state of the FSM. A network of the plurality of FSMs is established by providing communication links among individual ones of the plurality of FSMs according to the business rules. The communication links define the integration flow.