There are provided systems and methods for pressure sensitive device casing to cause device functionality. A computing device, such as a mobile smart phone, may include one or more pressure sensor devices mounted within, surrounding, or nearby structural components of the computing device, such as a device casing. A user may apply pressure input to the structure of the computing device, for example, through touch and force of touch to the device, where the pressure sensor may detect a presence and location of the input. The computing device may include a transaction processing application, where the input may be received during use of the application. The pressure of the input may further define the input for the application. For example, an input with a first pressure may cause a first process to be initiated, while a second pressure may cause a second process to be initiated.