The embodiment of the present invention discloses a control device of a display panel and a control method, wherein the control method of the display panel comprises: detecting a temperature of a chip of a source driver of the display panel, and to generate a notification signal according to the temperature; obtaining a temperature of the notification signal, and generating a control signal according to the temperature if the temperature exceeds preset temperature range thresholds; switching a polarity inversion manner of the display panel according to the control signal. The present invention adjusts the power consumption of the display panel by adjusting the polarity inversion manner so that the display panel can work with the proper power consumption. Thus, the chip of the source driver can be ensured to be in the normal work temperature range to guarantee the normal operation of the display panel and decrease of the failure.