Disclosed are a driving method and a driving device for reducing electromagnetic interference. A method for driving a source-chip on film S-COF and a timing controller TCON is provided as: the timing controller TCON first outputs initial data A stored in the source-chip on film S-COF; it is determined whether data received is correct by comparing transmission data received by the source-chip on film S-COF with initial data A built in the source-chip on film S-COF, and if a determination result is no, a swing value of transmission data mini-LVDS is adjusted by the timing controller TCON.