Method and system for active reduction of a predefined audio acoustic signal (AAAS), also referred to as “noise”, in a quiet zone, without interfering undefined acoustic noise signals within as well as outside the quiet zone, by generating accurate antiphase AAAS signal. The accuracy of the generated antiphase AAAS is obtained by employing a unique synchronization signal(s) (SYNC) which is generated and combined with the predefined AAAS. The combined signal is electrically transmitted (referred to as the “electric channel”) to a processing “quieting component”. Simultaneously, the generated SYNC signal is acoustically broadcasted near the predefined AAAS and merges with it. A microphone in the quiet zone receives the merged acoustic signals that arrive via the air (referred to as the “acoustical channel”) to the quiet zone and a receiver in the quieting component receives the combined electrical AAAS and SYNC signal that arrive wire or wireless to the quiet zone. In the quiet component the SYNC is detected from both electrical and acoustical channels, the detected SYNC signals with the electrically received AAAS signal are used to calculate the timing and momentary amplitude for generating an accurate acoustic antiphase AAAS signal to cancel the acoustic predefined AAAS. By continuously and periodically updating the SYNC signal enables to dynamically evaluate acoustical environmental distortions that might appear due to echo, reverberations, frequency non-linear response, or due to other distortions mechanisms.