A protection circuit for use in an RF active circuit includes a signal strength detecting circuit, a current detecting circuit, a logic circuit, and a switching unit. The signal strength detecting circuit is coupled to the signal input end or the signal output end of the RF active circuit and configured to generate a first detecting signal according to the signal strength of the RF signal. The current detecting circuit is configured to detect the VSWR of the RF signal based on the driving current of the RF active circuit, thereby generating a corresponding second detecting signal. The logic circuit is configured to generate a switch control signal according to the first detecting signal and the second detecting signal. The switching unit is configured to lower the driving current of the RF active circuit according to the switch control signal.