A wireless adapter front end system and method for an information handling system including a wireless adapter for communicating on a plurality antenna systems for connection to a plurality of concurrently operating wireless links with a controller executing code instructions for an antenna optimization system for detecting one or more active wireless links operating via the plurality of antenna systems where the controller receives a trigger input indicating an operating condition to determine whether an antenna adjustment is required among the plurality of antenna systems, wherein the trigger input may be selected from one or more indications of a shared communication frequency band, a radio aggregation operation, SAR proximity detection, or operation of a plurality of radio access technologies (RATs). The controller implementing an impedance adjustment of at least one of the plurality of wireless antenna systems to avoid interference between concurrently operating wireless links.