A control apparatus includes a signal readout unit 15 which reads out a frame image obtained from an image pickup device while the frame image is divided into a plurality of different regions, an image information calculating unit 16 which calculates image information based on an image signal of each of the plurality of different regions obtained from the signal readout unit, and an adjusting unit 17 which determines a target adjustment value of an image pickup unit including an image pickup optical system and the image pickup device based on the image information during capturing the frame image.