The present technique relates to a solid-state image pickup device capable of realizing low power consumption in a simpler configuration, a control method therefor, and an electronic apparatus. The solid-state image pickup device includes a pixel array section that has a plurality of pixels arranged two-dimensionally in a matrix shape, load transistors each of which configures a source follower circuit with an amplification transistor of each pixel of the pixel array section, and a control circuit that, in accordance with the amount of light received by one or more of the pixels, controls a supply voltage of each of the load transistors or controls a current flowing through each of the load transistors. The present technique can be applied to a solid-state image pickup device, for example.