A cylinder filling system is configured to automatically fill fluid cylinders with fluid at varying fluid pressures. The cylinder filling system may include a plurality of pressure control manifolds operatively connected together and disposed in a fluid circuit between a fluid storage container and a fluid outlet. A control unit may be in communication with the plurality of pressure control manifolds. The control unit is configured to operate the plurality of pressure control manifolds to deliver fluid at a rated fluid pressure of a fluid cylinder that connects to the fluid outlet.