Invention Grant
- Patent Title: Non-invasive method and system for measuring myocardial ischemia, stenosis identification, localization and fractional flow reserve estimation
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Application No.: US15633330Application Date: 2017-06-26
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Publication No.: US10362950B2Publication Date: 2019-07-30
- Inventor: Sunny Gupta , Shyamlal Ramchandani , Timothy Burton , William Sanders , Ian Shadforth
- Applicant: Analytics For Life
- Applicant Address: CA Toronto
- Assignee: Analytics For Life Inc.
- Current Assignee: Analytics For Life Inc.
- Current Assignee Address: CA Toronto
- Agency: Meunier Carlin & Curfman LLC
- Main IPC: A61B5/04
- IPC: A61B5/04 ; A61B5/026 ; A61B5/0408 ; A61B5/00 ; A61B5/02 ; A61B5/1455

Abstract:
The present disclosure facilitates the evaluation of wide-band phase gradient information of the heart tissue to assess, e.g., the presence of heart ischemic heart disease. Notably, the present disclosure provides an improved and efficient method to identify and risk stratify coronary stenosis of the heart using a high resolution and wide-band cardiac gradient obtained from the patient. The patient data are derived from the cardiac gradient waveforms across one or more leads, in some embodiments, resulting in high-dimensional data and long cardiac gradient records that exhibit complex nonlinear variability. Space-time analysis, via numeric wavelet operators, is used to study the morphology of the cardiac gradient data as a phase space dataset by extracting dynamical and geometrical properties from the phase space dataset.
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