Invention Grant
- Patent Title: Compositions and methods of inhibiting N-acylethanolamine-hydrolyzing acid amidase
-
Application No.: US15072194Application Date: 2016-03-16
-
Publication No.: US10363237B2Publication Date: 2019-07-30
- Inventor: Daniele Piomelli , Giorgio Tarzia , Marco Mor , Andrea Duranti , Andrea Tontini
- Applicant: The Regents of the University of California , Universita Degli Studi Di Urbino “Carlo Bo” , Universita Degli Studi Di Parma
- Applicant Address: US CA Oakland IT Urbino IT Parma
- Assignee: The Regents of the University of California,Universita Degli Studi Di Urbino “Carlo Bo”,Universita Degli Studi Di Parma
- Current Assignee: The Regents of the University of California,Universita Degli Studi Di Urbino “Carlo Bo”,Universita Degli Studi Di Parma
- Current Assignee Address: US CA Oakland IT Urbino IT Parma
- Agency: Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C.
- Agent Anson M. Nomura
- Main IPC: A61K31/337
- IPC: A61K31/337 ; A61K31/165 ; A61K31/195 ; A61K31/365 ; C07D305/10
Abstract:
Compounds and pharmaceutical compositions are contemplated that inhibit N-acyl-ethanolamine-hydrolyzing acid amidase (NAAA) to so increase the concentration of the substrate of NAAA, palmitoylethanolamide (PEA). NAAA inhibition is contemplated to be effective to alleviate conditions associated with a reduced concentration of PEA. Among other uses, various NAAA inhibitors are especially contemplated as therapeutic agents in the treatment of inflammatory diseases.
Public/Granted literature
- US20160256432A1 COMPOSITIONS AND METHODS OF INHIBITING N-ACYLETHANOLAMINE-HYDROLYZING ACID AMIDASE Public/Granted day:2016-09-08
Information query
