Invention Grant
- Patent Title: Stable and soluble formulations of receptor tyrosine kinase inhibitors, and methods of preparation thereof
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Application No.: US15880180Application Date: 2018-01-25
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Publication No.: US10363255B2Publication Date: 2019-07-30
- Inventor: Judit Horvath , Irina Astafieva , Signe Erickson , Kathleen Cogan Farinas
- Applicant: ForSight Vision4, Inc.
- Applicant Address: US CA Menlo Park
- Assignee: FORSIGHT VISION4, INC.
- Current Assignee: FORSIGHT VISION4, INC.
- Current Assignee Address: US CA Menlo Park
- Agency: Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C.
- Agent Edward D. Grieff
- Main IPC: A61K31/506
- IPC: A61K31/506 ; A61K9/00 ; A61K9/08 ; A61K47/32 ; A61K47/20 ; A61K47/40 ; A61K9/19 ; A61K47/69 ; A61K47/10 ; A61K47/18 ; A61M5/14
Abstract:
The present disclosure relates to stable formulations of receptor tyrosine kinase inhibitors (TKI), e.g., pazopanib; methods of preparation thereof; and use of the disclosed formulations in sustained delivery of the active agent to a target site. The disclosure further relates to methods of converting one polymorphic Form of a TKI to another polymorphic Form and/or an amorphous form.
Public/Granted literature
Information query
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