An actuator assembly for use in fire suppression systems for use in vehicle and industrial fire protection systems. The actuator assembly engages a cartridge of pressurized gas and releases the gas contained therein with a puncturing assembly. The actuator assembly includes a receptacle that controls the manner in which the actuator assembly and cartridge engage one another. The actuator assembly is configured for electrical and pneumatic actuation for rupturing the seal of the cartridge of pressurized gas. The actuator assembly has a housing that includes at least one inlet port that is coupled to a pressurized gas source, which is formed between a first chamber for electrical components sealed from the operative environment of the actuator assembly and a second chambers for the puncturing assembly. The actuator assembly allows for serial interconnection of multiple actuator assemblies for operation by a single source of pressurized gas.