Method and apparatus are disclosed for control module activation of vehicles in a key-off state. An example system includes a vehicle at a location in a key-off state that includes a battery, a communication module, and an infotainment unit to activate and present media responsive to the communication module receiving an activation signal. The example system also includes a remote processor to determine a charge level of the battery, identify a parking duration for the location, and send the activation signal responsive to the charge level being less than a threshold associated with the parking duration.