Invention Grant
- Patent Title: Conformationally-preorganized, miniPEG-containing gamma-peptide nucleic acids
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Application No.: US16145075Application Date: 2018-09-27
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Publication No.: US10364272B2Publication Date: 2019-07-30
- Inventor: Danith H. Ly , Srinivas Rapireddy , Bichismita Sahu
- Applicant: CARNEGIE MELLON UNIVERSITY
- Applicant Address: US PA Pittsburgh
- Assignee: CARNEGIE MELLON UNIVERSITY
- Current Assignee: CARNEGIE MELLON UNIVERSITY
- Current Assignee Address: US PA Pittsburgh
- Agency: Foley & Lardner LLP
- Main IPC: C07H15/00
- IPC: C07H15/00 ; C07K14/00 ; C07D473/34 ; C07D473/18 ; C07D239/54 ; C07D239/47 ; C08G69/10 ; A61K47/60 ; C07K1/04 ; C07C271/20 ; C07C229/12 ; C07K1/08

Abstract:
The present invention relates to γ-PNA monomers according to Formula I where substituent groups R1, R2, R3, R4, R5, R6, B and P are defined as set forth in the specification. The invention also provides methodology for synthesizing compounds according to Formula I and methodology for synthesizing PNA oligomers that incorporate one or more Formula I monomers.
Public/Granted literature
- US20190062378A1 CONFORMATIONALLY-PREORGANIZED, MiniPEG-CONTAINING GAMMA-PEPTIDE NUCLEIC ACIDS Public/Granted day:2019-02-28
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