Invention Grant
- Patent Title: Cytomegalovirus antigens
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Application No.: US15533483Application Date: 2015-12-07
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Publication No.: US10364273B2Publication Date: 2019-07-30
- Inventor: Andrea Carfi , Sumana Chandramouli , Ethan C. Settembre
- Applicant: GLAXOSMITHKLINE BIOLOGICALS SA
- Applicant Address: BE
- Assignee: GLAXOSMITHKLINE BIOLOGICALS S.A.
- Current Assignee: GLAXOSMITHKLINE BIOLOGICALS S.A.
- Current Assignee Address: BE
- Priority: EP14196854 20141208
- International Application: PCT/IB2015/059420 WO 20151207
- International Announcement: WO2016/092460 WO 20160616
- Main IPC: C07K14/005
- IPC: C07K14/005 ; A61K39/12 ; A61K39/245 ; A61K39/00
Abstract:
The invention generally relates to recombinant human cytomegalovirus (CMV) gB proteins and immunogenic fragments thereof, which do not comprise a transmembrane (TM) domain; and comprise one or more mutations that reduce the aggregation between the monomeric trimers of gB, and/or adhesion of the monomeric trimer of gB to the host cell.
Public/Granted literature
- US20180265551A1 CYTOMEGALOVIRUS ANTIGENS Public/Granted day:2018-09-20
Information query
