Invention Grant
- Patent Title: Methods of preparation of conjugates
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Application No.: US15677846Application Date: 2017-08-15
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Publication No.: US10364294B2Publication Date: 2019-07-30
- Inventor: Nathan Elliott Fishkin , Michael Louis Miller , Wei Li , Rajeeva Singh
- Applicant: IMMUNOGEN, INC.
- Applicant Address: US MA Waltham
- Assignee: IMMUNOGEN, INC.
- Current Assignee: IMMUNOGEN, INC.
- Current Assignee Address: US MA Waltham
- Agency: McCarter & English, LLP
- Agent Yu Lu; Xin Zhang
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K45/06 ; A61K47/54 ; A61K47/68 ; C07K16/30 ; C07D487/04 ; C07D519/00 ; A61K31/5517
Abstract:
The present invention is directed to methods of preparing a conjugate of a cell-binding agent and a drug (such as a cytotoxic compound). The methods comprise the use of an imine reactive compound to enable efficient conjugations of cytotoxic compounds with cell binding agents.
Public/Granted literature
- US20180037659A1 METHODS OF PREPARATION OF CONJUGATES Public/Granted day:2018-02-08
Information query
