Invention Grant
- Patent Title: Antibodies specific for MMP9
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Application No.: US15503447Application Date: 2015-08-13
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Publication No.: US10364296B2Publication Date: 2019-07-30
- Inventor: Yolande Chvatchko Missotten , Laurence Goffin , Olivier Leger , Steven M. Dunn , Christine Power , Kinsey Maundrell
- Applicant: CALYPSO BIOTECH SA , MERCK PATENT GMBH
- Applicant Address: CH Plan-les-Ouates DE Darmstadt
- Assignee: CALYPSO BIOTECH SA,MERCK PATENT GMBH
- Current Assignee: CALYPSO BIOTECH SA,MERCK PATENT GMBH
- Current Assignee Address: CH Plan-les-Ouates DE Darmstadt
- Agency: Saliwanchik, Lloyd & Eisenschenk
- Priority: EP14180765 20140813
- International Application: PCT/EP2015/068645 WO 20150813
- International Announcement: WO2016/023979 WO 20160218
- Main IPC: C07K16/40
- IPC: C07K16/40 ; G01N33/53 ; C12N15/13 ; G01N33/573 ; A61K39/00
Abstract:
The present invention relates to new proteins that bind to MMP9 and comprise at least one fragment of a heavy chain variable region and/or at least one fragment of a light chain variable region of an antibody. In particular, the MMP9 binding proteins according to the invention are able to neutralize MMP9 activity and are useful in the prevention and/or treatment of inflammatory and/or autoimmune diseases or cancers. In particular, the MMP9 binding proteins according to the invention are useful in diagnosis of MMP9-related disorders.
Public/Granted literature
- US20170233495A1 ANTIBODIES SPECIFIC FOR MMP9 Public/Granted day:2017-08-17
Information query
