Invention Grant
- Patent Title: Identification of a JAK2 mutation in polycythemia vera
-
Application No.: US14164880Application Date: 2014-01-27
-
Publication No.: US10364430B2Publication Date: 2019-07-30
- Inventor: William Vainchenker , Valerie Ugo , Chloe James , Jean-Pierre Le Couedic , Nicole Casadevall
- Applicant: Institut Gustave-Roussy , INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE SCIENTIFIQUE MEDICALE (INSERM) , ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS , UNIVERSITE DE VERSAILLES—ST QUENTIN EN YVELINES , UNIVERSITE PARIS-SUD
- Applicant Address: FR Paris FR Paris FR Villejuif FR Versailles FR Orsay
- Assignee: ASSISTANCE PUBLIQUE—HOPITAUX DE PARIS,INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM),INSTITUT GUSTAVE-ROUSSY,UNIVERSITE DE VERSAILLES—ST QUENTIN EN YVELINES,UNIVERSITE PARIS-SUD
- Current Assignee: ASSISTANCE PUBLIQUE—HOPITAUX DE PARIS,INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM),INSTITUT GUSTAVE-ROUSSY,UNIVERSITE DE VERSAILLES—ST QUENTIN EN YVELINES,UNIVERSITE PARIS-SUD
- Current Assignee Address: FR Paris FR Paris FR Villejuif FR Versailles FR Orsay
- Agency: Potomac Law Group, PLLC
- Priority: FR0411480 20041027
- Main IPC: C12N9/12
- IPC: C12N9/12 ; C12N15/113 ; C12Q1/6813 ; C12Q1/6883 ; G01N33/574
Abstract:
The present invention concerns the V617F variant of the protein-tyrosine kinase JAK2, said variant being responsible for Vaquez Polyglobulia. The invention also relates to a first intention diagnostic method for erythrocytosis and thrombocytosis allowing their association with myeloproliferative disorders, or to the detection of the JAK2 V617F variant in myeloproliferative disorders allowing their reclassification in a new nosological group.
Public/Granted literature
- US20150051263A2 IDENTIFICATION OF A JAK2 MUTATION IN POLYCYTHEMIA VERA Public/Granted day:2015-02-19
Information query
