Invention Grant
- Patent Title: Chromophoric structures for lanthanide chelates
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Application No.: US15308458Application Date: 2015-04-24
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Publication No.: US10365286B2Publication Date: 2019-07-30
- Inventor: Harri Takalo
- Applicant: RADIOMETER TURKU OY
- Applicant Address: FI Turku
- Assignee: Radiometer Turku Oy
- Current Assignee: Radiometer Turku Oy
- Current Assignee Address: FI Turku
- Agency: Finnehan, Henderson, Farabow, Garrett & Dunner, LLP
- Priority: DK201400242 20140502
- International Application: PCT/EP2015/058970 WO 20150424
- International Announcement: WO2015/165826 WO 20151105
- Main IPC: G01N33/58
- IPC: G01N33/58 ; C09K11/06 ; G01N21/64

Abstract:
The present application discloses novel lanthanide chelate designs (Formula (I) and Formula (III)) having fluorenyl-, fluorenylethynyl, 9H-carbazolyl-, 9H-carbozolylethynyl-, dibenzothiophenyl-, dibenzothiophenylethynyl-, dibenzofuranyl or dibenzofuranylethynyl pyridine chromophores around an emitting lanthanide ion, e.g. an europium(III) ion. The three-membered ring chromophores exhibit high molar absorptivity and luminescence with lanthanide ions. The application also discloses a detectable molecule comprising a biospecific binding reactant useful in bioaffinity based binding assay, luminescent lanthanide chelating ligands, as well as a solid support conjugated with the chelates.
Public/Granted literature
- US20170089913A1 NEW CHROMOPHORIC STRUCTURES FOR LANTHANIDE CHELATES Public/Granted day:2017-03-30
Information query
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