An information handling system input device coordinates presentation of keyboard augmentation panels proximate a keyboard resting on a horizontally-disposed touchscreen display. The keyboard augmentation panels relate keyboard and other inputs to an application active on the information handling system to enhance end user interactions. A keyboard augmentation module tracks the keyboard position on the touchscreen display to adapt content presentation in the keyboard augmentation panels based upon expected end user inputs. In other embodiments, other physical devices are augmented to have hybrid graphical interfaces that enhance multi-hand end user interactions.