In a wireless communication system including a wireless transmit/receive unit (WTRU) and at least one Node-B, a method and apparatus is used to selectively enable reception of at least one downlink (DL) enhanced uplink (EU) signaling channel established between the WTRU and the Node-B(s). During the operation of an enhanced dedicated channel (E-DCH), the WTRU monitors at least one DL EU signaling channel established between the WTRU and the Node-B(s) only when it is necessary, based on the WTRU's knowledge of at least one established standard procedure. The WTRU coordinates and consolidates DL signaling channel reception requirements of a plurality of channel allocation and/or data transmission procedures carried out by the WTRU in accordance with the established standard procedure. The WTRU determines whether to enable reception of at least one specific DL signaling channel based on the consolidated DL signaling channel reception requirements.