Invention Grant
- Patent Title: Phenyl linked quinolinyl modulators of RORγt
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Application No.: US15182231Application Date: 2016-06-14
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Publication No.: US10369146B2Publication Date: 2019-08-06
- Inventor: Kristi A. Leonard , Kent Barbay , James P. Edwards , Kevin D. Kreutter , David A. Kummer , Umar Maharoof , Rachel Nishimura , Maud Urbanski , Hariharan Venkatesan , Aihua Wang , Ronald L. Wolin , Craig R. Woods , Anne Fourie , Xiaohua Xue , Maxwell D. Cummings
- Applicant: Janssen Pharmaceutica NV
- Applicant Address: BE Beerse
- Assignee: Janssen Pharmaceutica NV
- Current Assignee: Janssen Pharmaceutica NV
- Current Assignee Address: BE Beerse
- Agent Yuriy P. Stercho
- Main IPC: A61K31/4709
- IPC: A61K31/4709 ; A61K31/506 ; A61K45/06 ; C07D417/14 ; C07D401/06 ; C07D401/14 ; C07D409/14

Abstract:
The present invention comprises compounds of Formula I. wherein: R1, R2, R3, R4, R5, R6, R7, R8, and R9 are defined in the specification. The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating RORγt activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1.
Public/Granted literature
- US20160279122A1 PHENYL LINKED QUINOLINYL MODULATORS OF RORgammat Public/Granted day:2016-09-29
Information query
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