The invention discloses a base for a novel accelerator therapy device. A boat-shaped rocker arm is creatively utilized to drive a main frame to rotate around an X axis, and meanwhile an accelerator simultaneously follows the main frame to rotate around a Z axis, so that the accelerator runs on a spherical surface and irradiates an isocentric lesion in any direction of a three-dimensional spherical space; the center of gravity of the boat-shaped rocker arm is low, the boat-shaped rocker arm bears weight on the curved surface, and a rotating shaft and an upright post for bearing the weight of the main frame and the weight of the accelerator in the prior art are removed, so that the base is high in stability, safe, reliable and low in requirement for transmission equipment and easily realizes industrialized application.