Invention Grant
- Patent Title: Optimized factor VIII gene
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Application No.: US14767425Application Date: 2014-02-14
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Publication No.: US10370431B2Publication Date: 2019-08-06
- Inventor: Siyuan Tan , Robert T. Peters
- Applicant: Bioverativ Therapeutics Inc.
- Applicant Address: US MA Waltham
- Assignee: Bioverativ Therapeutics Inc.
- Current Assignee: Bioverativ Therapeutics Inc.
- Current Assignee Address: US MA Waltham
- Agency: Lathrop Gage LLP
- Agent James H. Velema, Esq.
- International Application: PCT/US2014/016441 WO 20140214
- International Announcement: WO2014/127215 WO 20140821
- Main IPC: C07K14/755
- IPC: C07K14/755 ; C12N9/64

Abstract:
The present invention provides codon optimized Factor VIII sequences, vectors and host cells comprising codon optimized Factor VIII sequences, polypeptides encoded by codon optimized Factor VIII sequences, and methods of producing such polypeptides.
Public/Granted literature
- US20150361158A1 Optimized Factor VIII Gene Public/Granted day:2015-12-17
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