Invention Grant
- Patent Title: Engineered imine reductases and methods for the reductive amination of ketone and amine compounds
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Application No.: US15519949Application Date: 2015-11-24
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Publication No.: US10370648B2Publication Date: 2019-08-06
- Inventor: Oscar Alvizo , Melissa Ann Mayo , Jeffrey C. Moore
- Applicant: Codexis, Inc.
- Applicant Address: US CA Redwood City
- Assignee: Codexis, Inc.
- Current Assignee: Codexis, Inc.
- Current Assignee Address: US CA Redwood City
- Agency: Codexis, Inc.
- International Application: PCT/US2015/062300 WO 20151124
- International Announcement: WO2016/085916 WO 20160602
- Main IPC: C12N9/06
- IPC: C12N9/06 ; C12P13/00 ; C07K14/195
Abstract:
The present application provides engineered polypeptides having imine reductase activity, polynucleotides encoding the engineered imine reductases, host cells capable of expressing the engineered imine reductases, and methods of using these engineered polypeptides with a range of ketone and amine substrate compounds to prepare secondary and tertiary amine product compounds.
Public/Granted literature
- US20170355966A1 ENGINEERED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION OF KETONE AND AMINE COMPOUNDS Public/Granted day:2017-12-14
Information query
