Invention Grant
- Patent Title: Methods and compositions for the specific inhibition of alpha-1 antitrypsin by double-stranded RNA
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Application No.: US15247201Application Date: 2016-08-25
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Publication No.: US10370655B2Publication Date: 2019-08-06
- Inventor: Bob D. Brown , Henryk T. Dudek
- Applicant: Dicerna Pharmaceuticals, Inc.
- Applicant Address: US MA Cambridge
- Assignee: Dicerna Pharmaceuticals, Inc.
- Current Assignee: Dicerna Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Polsinelli PC
- Main IPC: C12N15/11
- IPC: C12N15/11 ; C12N15/113
Abstract:
This invention relates to compounds, compositions, and methods useful for reducing α-1 antitrypsin target RNA and protein levels via use of dsRNAs, e.g., Dicer substrate siRNA (DsiRNA) agents.
Public/Granted literature
- US20170130221A1 METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF ALPHA-1 ANTITRYPSIN BY DOUBLE-STANDED RNA Public/Granted day:2017-05-11
Information query
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