Invention Grant
- Patent Title: Methods of using O-methyltransferase for biosynthetic production of pterostilbene
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Application No.: US15033705Application Date: 2014-11-03
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Publication No.: US10370683B2Publication Date: 2019-08-06
- Inventor: Mohammad Wadud Bhuiya , Yechun Wang , Xiaodan Yu
- Applicant: CONAGEN INC.
- Applicant Address: US MA Bedford
- Assignee: Conagen Inc.
- Current Assignee: Conagen Inc.
- Current Assignee Address: US MA Bedford
- Agency: Wolf, Greenfield & Sacks, P.C.
- Agent Karen K. Chan
- International Application: PCT/US2014/063682 WO 20141103
- International Announcement: WO2015/066609 WO 20150507
- Main IPC: C12P7/22
- IPC: C12P7/22 ; C12N9/10 ; C12N9/00
Abstract:
A biosynthetic method of making pterostilbene including expressing a 4-coumaratexoenzyme A ligase (4CL) in a cellular system, expressing a stilbene synthase (STS) in the cellular system, expressing a resveratrol O-methyltransferase (ROMT) in the cellular system, feeding p-coumaric acid to the cellular system, growing the cellular system in a medium, and producing pterostilbene.
Public/Granted literature
- US20160273006A1 METHODS OF USING O-METHYLTRANSFERASE FOR BIOSYNTHETIC PRODUCTION OF PTEROSTILBENE Public/Granted day:2016-09-22
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