- Patent Title: Propeptide-luciferase fusion proteins and methods of use thereof
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Application No.: US15600475Application Date: 2017-05-19
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Publication No.: US10370697B2Publication Date: 2019-08-06
- Inventor: Sean Burns , David Altshuler , Amedeo Vetere
- Applicant: THE BROAD INSTITUTE, INC. , The General Hospital Corporation , INSTITUTO CARLOS SLIM DE LA SALUD, A.C.
- Applicant Address: US MA Cambridge US MA Boston MX Mexico City
- Assignee: THE BROAD INSTITUE, INC.,THE GENERAL HOSPITAL CORPORATION,INSTITUTO CARLOS SLIM DE LA SALUD, A.C.
- Current Assignee: THE BROAD INSTITUE, INC.,THE GENERAL HOSPITAL CORPORATION,INSTITUTO CARLOS SLIM DE LA SALUD, A.C.
- Current Assignee Address: US MA Cambridge US MA Boston MX Mexico City
- Agency: Burns & Levinson LLP
- Agent Christopher R. Cowles, J.D.
- Main IPC: C12N9/02
- IPC: C12N9/02 ; C12Q1/66 ; C07K14/62 ; G01N33/50 ; G01N33/58 ; C07K14/575 ; C07K14/605 ; C12Q1/6897
Abstract:
The present invention provides nucleic acid constructs that encode fusion peptides comprising a bioluminescent protein and a precursor of a secreted peptide or protein expressed at the cell surface and high throughput screening assays using same.
Public/Granted literature
- US20170260565A1 PROPEPTIDE-LUCIFERASE FUSION PROTEINS AND METHODS OF USE THEREOF Public/Granted day:2017-09-14
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