The present invention discloses a system for consolidating soft clay by combined anode boosting and electro-osmosis, comprising a vacuum preloading system, wherein the vacuum preloading system comprises anode tubes, cathode tubes, a power supply, a boosting device, sealing cloth and a pumping and drainage device; the sealing cloth is covered above soft clay; air vents are formed on side faces of the cathode tubes and the anode tubes; the cathode tubes and the anode tubes are connected to a boosted pumping and drainage pipe above the soft clay through pipelines; the boosted pumping and drainage pipe is configured with the boosting device and the pumping and drainage device; and, the anode tubes and the cathode tubes are connected to an anode and a cathode of the power supply, respectively. The present invention further provides a method for consolidating soft clay by using the system for consolidating soft clay by combined anode boosting and electro-osmosis. In the present invention, after the anode tubes are configured with a boosting device, a gas can be fed into the anode tubes; under the combined action of the high-pressure gas and the anode tubes, water is squeezed to the cathode tubes, so that water can be drained from the soil more thoroughly.