A method for carrying out two-field nuclear magnetic resonance (=2FNMR) measurements involves preparing a sample (9a) in a first working volume (5) of a highly homogeneous magnetic field with a first field strength; transferring the sample (9a) to a second working volume (7) with a magnetic field having lower homogeneity and having a second field strength, wherein the first field strength is at least 2 Tesla larger than the second field strength; manipulating the sample (9a) at the second working volume (7) by applying a sequence of radio-frequency (=RF) and/or field gradient pulses; transferring the sample (9a) back to the first working volume (5); and detecting an NMR signal of the sample (9a) in the first working volume (5). The method allows for NMR experiments with which more and/or improved quality information about an investigated sample can be obtained.