An anti-counterfeiting serialization method. The method can include receiving an input serial number, locating a seed character at a predetermined position in the input serial number, determining, based on the seed character, a first output position for an incrementing character of the input serial number, determining, based on the incrementing character, at least one second output position for at least one remaining character of the input serial number, and generating an output serial number having the incrementing character in the first output position and at least one remaining character in the at least one second output position.