Techniques described herein are directed to position determination of a user equipment (UE) in an asynchronous wireless network, such as a 4G or 5G network. In one embodiment, a base station measures real time differences (RTDs) to neighboring base stations and a Round Trip signal propagation Time (RTT) to the UE and receives Reference Signal Time Difference (RSTD) measurements from the UE, whereby a location of the UE is determined using the RTD measurements, RTT measurement and RSTD measurements. In other embodiments, the UE may obtain the RTT and RSTD measurements and may receive RTD measurements from a base station, whereby a location of the UE is determined by the UE or by a location server.