Examples disclosed herein relate to airflow control in data centers utilizing hot aisle containment. Consistent with some embodiments disclosed herein, a first differential pressure sensor may be located in a contained hot aisle in a data center and a second differential pressure sensor may be located in an above-ceiling hot air return plenum connected to the contained hot aisle. Pressure sensor data obtained from the differential pressure sensors may be used to maintain a near-neutral pressure in the contained hot aisle and a set negative pressure in the hot air return plenum.