Invention Grant
- Patent Title: Process and intermediates
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Application No.: US15780957Application Date: 2016-12-08
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Publication No.: US10377697B2Publication Date: 2019-08-13
- Inventor: Florian Karl Kleinbeck-Riniker , Benjamin Martin , Gerhard Penn , Francesco Venturoni , Thierry Schlama , Thomas Ruch , Thomas Allmendinger , Bernhard Wietfeld , Paolo Filipponi
- Applicant: Novartis AG
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agent Judith D. Kuntz
- Priority: EP15199378 20151210; EP16198655 20161114
- International Application: PCT/IB2016/057435 WO 20161208
- International Announcement: WO2017/098430 WO 20170615
- Main IPC: C07C51/373
- IPC: C07C51/373 ; C07C69/738 ; C07C313/06 ; C07C229/34 ; C07D265/02 ; C07D207/36 ; C07C251/40 ; C07C251/66 ; C07C59/84 ; C07C67/035

Abstract:
The present invention relates to a new chemical synthesis, intermediates and catalysts useful for the preparation of the neprilysin (NEP) inhibitor sacubitril. It further relates to new intermediate compounds and their use for said new chemical synthesis route.
Public/Granted literature
- US20180354889A1 NEW PROCESS AND INTERMEDIATES Public/Granted day:2018-12-13
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