An off-axis aspheric three-mirror optical system comprises a primary mirror, a secondary mirror, and a tertiary mirror. Relative to a first three-dimensional rectangular coordinates system in space, a second three-dimensional rectangular coordinates system is defined by a primary mirror location, a third three-dimensional rectangular coordinates system is defined by a secondary mirror location, and a fourth three-dimensional rectangular coordinates system is defined by a tertiary mirror location. The primary mirror in the second three-dimensional rectangular coordinates system, the secondary mirror in the third three-dimensional rectangular coordinates system, and the tertiary mirror in the fourth three-dimensional rectangular coordinates system are all sixth-order polynomial aspheric.